- Fetal Upturned Nose
- IgA Nephropathy in Pregnancy
- Umbilical vein varix
- Timing of Cranial Markers in Open NTD
- Real world experience Open Neural tube defect and Brain Signs
- Real world experience First Trimester Megacystis – Management
- Real world experience Fetal Megacystis
- Abnormal facial profile
- Azygous Vein & ARSA
- Blakes Pouch Cyst
- Absent nasal bone (ANB)
- Choroid plexus cysts
- Chronic placental abruption
- Fetal Alcohol Syndrome
- Placenta-First Risk Stratification
- AVSD
- Blakes Pouch Cyst
- Confined Placental Mosaicism
- Echogenic Bowel
- Fetal Anemia
- Fetal Club Foot
- Fetal Mild Micromelia
- Hypochondroplasia – Mild Micromelia
- Hypoplastic Nasal Bone
- IgM IgG IgG Avidity
- Increased Nuchal Translucency
- Isotretinoin in Pregnancy
- Partial agenesis of corpus callosum
- PGT A
- PGT-A Mosaicism to CPM
- Placenta First - CPM
- Radiation exposure during pregnancy
- Real world Chorionic bump experience
- Real world Fetal Isotretinoin exposure
- Real world Increased Nuchal Translucency & Genetic RISK
- Real world Renal Pyelectasis
- Real world Transient NT & Cystic Hygroma
- Real world Transient NT
- Renal Pyelectasis or Extra Renal Pelvis
- Right And Double Aortic Arch
- Short Femur Length Foot FL ratio
- Y Microdeletion
- CCAM CPAM
- Coffin–Siris syndrome
- Congenital CMV Infection
- Increased NT and Localized CHAOS
- Indomethacin and Reduction for AFI
- Atrioventricular septal defect (AVSD)
- Choledochal cyst & Cystic biliary atresia
- Duodenal Atresia
- Fetal atrial bigeminy
- Fetal Dilated stomach
- Mutation Types in DMD
- Risk of rubella in nonimmune pregnant woman
- Salt-losing nephropathy
- Syndromic Cystic biliary atresia
- TGA DORV TOF CCTGA
- Unilateral echogenic kidney with polyhydramnios
- Unilateral renal agenesis, Ectopic, Cross fused kidney
Chorionic bump
A chorionic bump is a focal convex protrusion from the chorionic wall into the gestational sac cavity, seen in the first trimester.
It appears as:
- A bulge projecting into the sac
- Often echogenic or mixed echogenic
- No internal vascularity on Doppler
- Usually adjacent to the chorionic/placental surface
It is most commonly detected between 6–11 weeks.
Pathophysiology
- A localized hematoma within the developing chorion
- Possibly due to failed implantation remodeling
- Focal placental hemorrhage or infarction
Histopathology
- Organized hematoma
- Fibrin deposition
It is a contained chorionic hematoma protruding inward, not a fetal structure.
Incidence
Reported incidence:
- ~0.4–0.7% of early pregnancy scans
It is detected more often.
Sonographic appearance
Typical features:
- Round or oval protrusion
- Projects into gestational sac
- No Doppler flows
- Usually, single
- Yolk sac and embryo separate from it
Differential Diagnosis:
- Subchorionic hematoma (which lies between chorion and uterine wall)
- Placental mass
- Molar change (very different pattern)
Association with miscarriage
- Increased risk of first-trimester pregnancy loss
- Miscarriage rates reported between 20–50% in some series
- Risk higher if:
- Multiple bumps
- Large bump
- Absent fetal cardiac activity
- Small gestational sac
However, many pregnancies with a chorionic bump continue normally.
Why increased risk of miscarriage?
- Abnormal placentation
- Localized placental vascular compromise
- Early implantation defect
Higher risk if:
- Large bump (>10–15 mm)
- Multiple bumps
- Increasing size over serial scans
Small, isolated bumps with good cardiac activity have better prognosis.
If pregnancy continues beyond first trimester
If fetal heartbeat persists and pregnancy progresses beyond 12–14 weeks:
- Prognosis improves significantly
- Many go on to normal outcomes
However
- Slightly higher risk of:
- Fetal growth restriction
- Preterm birth
- Placental complications
Aneuploidy association?
No strong consistent link with chromosomal abnormalities.
It is generally considered a placental phenomenon rather than genetic.
“This is a small collection within the early placenta. It is associated with a somewhat increased risk of miscarriage in the first trimester, but many pregnancies with this finding continue normally.”
Favorable prognosis
- Single bump
- Small size
- Strong fetal cardiac activity
- Appropriate crown-rump growth
- No subchorionic hematoma
- No vaginal bleeding
Unfavorable prognosis
- No cardiac activity
- Slow CRL growth
- Sac too small for embryo
- Multiple bumps
- Rapid increase in size
- Heavy bleeding
Chorionic bump is:
- Rare
- Likely focal placental hematoma
- Associated with increased early miscarriage risk
- Not necessarily predictive of poor second-trimester outcome if pregnancy progresses
If viable embryo with normal growth and isolated single small chorionic bump:
→ Risk of miscarriage is increased compared to baseline
→ But majority of ongoing pregnancies beyond first trimester do well